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Ionotropic glutamate receptor that functions being a cation permeable ligand-gated ion channel, gated by L-glutamate and also the glutamatergic agonist kainic acid. L-glutamate acts being an excitatory neurotransmitter at lots of synapses within the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformatio